Clinical Trials
We are leaders in the field of oncology
Northwest Oncology takes pride in being the leader in the field of oncology. Clinical trials are an essential process in finding new treatments and surgical procedures and detecting, preventing or treating new diseases.
We are affiliated with various organizations such as: the National Surgical Adjuvant Breast and Bowel Program (NSABP), Gynecologic Oncology Group (GOG), Hoosier Oncology Group (HOG), and Cancer Trials Support Unit (CTSU).
Affiliations
- Federal clinical research sponsored by the National Surgical Adjuvant Breast and Bowel Program (NSABP) for breast and colon cancer.
- Federal clinical research sponsored by the Gynecologic Oncology Group (GOG) for gynecological cancers.
- Phase II clinical trials sponsored by the Hoosier Oncology Group (HOG) for a variety of metastatic cancers.
- Phase III clinical trials sponsored by the Cancer Trials Support Unit (CTSU) supported by the National Cancer Institute.
Our Clinical Trials
Explore our cancer clinical trials programs below:
High Risk Breast Cancer
Status: On Hold
Protocol Title: A211102
Testing for Atypia in Random Perareolar Fine Needle Aspiration (RPFNA) Cytology after 12 months Metformin (1, 1-Dimethylbigunide Hydorchloride) Chemoprevention versus Placebo Control in Premenopausal Women.
Screening Breast Cancer
Status: Active
Protocol Title: EA1151
Tomosynthesis Mammographic Imaging Screening Trial (TMIST)
Breast Cancer (Adjuvant)
Status: Active
Protocol Title: A011401
Randomized Phase III Trial Evaluating the Role of Weight Loss In Adjuvant Treatment of Overweight and Obese Women with Early Breast Cancer
Breast Cancer (Adjuvant)
Status: Active
Protocol Title: A011502
A Randomized Phase III Double-Blinded Placebo Controlled Trial of Aspirin as Adjuvant Therapy for Node Positive HER2 Negative Breast Cancer: The ABC Trial.
Breast Cancer (Triple Negative)
Status: Active
Protocol Title: ECOG EA1131
A Randomized Phase III Post-Operative Trial of Platinum Based Chemotherapy vs Capecitabine in Patients with Residual Triple-Negative Basal-Like Breast cancer following Neoadjuvant Chemotherapy
Breast Cancer (Triple Negative)
Status: Active
Protocol Title: NRG BR003
A Randomized Phase III Trial of Adjuvant Therapy Comparing Doxorubicin Plus Cyclophosphamide Followed by Weekly Paclitaxel with or without Carboplatin for Node-Positive or High-Risk Node-Negative Triple-Negative Invasive Breast Cancer
Metastatic Triple Negative Breast Cancer
Status: Active
Protocol Title: NRG BR004
A Randomized, Double-Blind, Phase III Trial of Paclitaxel/Trastuzumab/Pertuzumab with Atezolizumab or Placebo in First-Line HER2-Positive Metastatic Breast Cancer
Breast Cancer (Metastic HER2+)
Status: Active
Protocol Title: Daiichi Sankyo, Inc/ DS8201-301
A Phase 3, multicenter, randomized, open-label, active-controlled study of DS-8201a, an anti-HER2-antibiody drug conjugate, versus treatment of investigator's choice for HER2-positvie, unresectable and/or metastatic breast cancer subjects pretreated with prior standard of care HER2 therapies, including T-DM1
Lung (Adjuvant)-NSLC, tissue study for ALK or EGFR
Status: Active
Protocol Title: ALCHEMIST (A151216)
Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial
Lung (Adjuvant)-NSCLC if ALK + for A151216 study
Status: Active
Protocol Title: ALCHEMIST (E4512)
A Phase III Double-Blind Trial for Surgically Resected Early Stage Non-Small Cell Lung Cancer: Crizotinib versus Placebo for Patients with Tumors Harboring the Anaplastic Lymphoma Kinase (ALK) Fusion Protein.
Lung (Adjuvant)-NSCLC, State IB-IIIA,If EGFR + in A151216 study
Status: Active
Protocol Title: ALCHEMIST (A081105)
Randomized Double Blind Placebo Controlled Study of Erlotinib or Placebo in Patients with Completely Resected Epidermal Growth Factor Receptor (EGFR) Mutant Non-small Cell Lung Cancer (NSCLC)
Ovarian (Stage II or IV)
Status: Active
Protocol Title: NRG GY005
A Randomized Phase II/III study of the combination of Cediranib and Olaparib compared to Cediranib or Olaparib alone, or standard of care chemotherapy in women with recurrent platinum-resistant or refractory ovarian, fallopian tube, or primary peritoneal cancer (COCOS)
Cervical Cancer (Locally Advanced)
Status: Coming June/July 2020
Protocol Title: MK3475-A18/ ENGOT-cx11
A Randomized, Phase 3, Double-Blind Study of Chemoradiotherapy with or without Pembrolizumab For The Treatment of High-Risk, Locally Advanced Cervical Cancer (KEYNOTE-A18/ENGOT-cx11)
Head/Neck Cancer
Status: Coming June/July 2020
Protocol Title: EA3161
A Phase II/III Randomized Study of maintenance Nivolumab versus Obversation In Patient with Locally Advanced, Intermediate Risk HPV positive OPCA (oral pharangeal cancer)
High Risk Breast Cancer
Status: Coming June/July 2020
Protocol Title: Caris
Biorespoistory-Prep-Breast Biopsy
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